General Cell Lines and Cell Cultures
Abcam CGP 7930, Positive allosteric modulator of GABAB receptors, 10MG
MW 292.5 Da, Purity >98%. Positive GABAB receptor allosteric modulator (EC50 values are 5.37 and 4.60 μM, respectively). Increases receptor agonist affinity and signal transduction efficacy. Also shown to potentiate receptor response to baclofen (ab120325).
The product is subject to the following: Abcam Restricted Use Statement
ATCC Quantitative Genomic DNA; from Candida tropicalis
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine fungal load and for other molecular biology applications.
Biolegend APC/FireTM 750 anti-mouse CD18
APC/Fire™ 750 anti-mouse CD183 (CXCR3) [CXCR3-173]; Isotype: Armenian Hamster IgG; Reactivity: Mouse; Apps: FC; Size: 100 μg
Amsbio LLC Luciferase & RFP Expression Hela cells (Neo)
Luciferase & RFP Expression Hela cells (Neo)
Eurofins Discoverx PrecisION hnAChR α1/β1/δ/ε Recombinant Stable Cell Line, 2 vials. (CYL3052)
The PrecisION hnAChR α1/β1/δ/ε Recombinant Stable Cell Line is a stable, engineered cell line for use in studying nAChR α1/β1/δ/ε ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses nAChR α1/β1/δ/ε ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Biochain Institute Inc Matched Pair - Frozen Tissue Section - Human Primary Tumor and Normal (PP): Kidney, 5 x2 slides /PK
BioChain's tissue products are based on the sample repository network established following the ethical standard and IRB-approved procedures. During the collection, the excised tissues are immediately put into liquid nitrogen and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. Human frozen tissue section matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of frozen tissue sections of primary tumor and its adjacent normal tissue; PM consists of frozen tissue sections of primary tumor and corresponding metastatic tumor. Frozen tissue sections in each pair are prepared from the same donor. This product line is ideal for localization of tumor-specific genes and tumor metastatic genes.
ATCC Pfizer Pneumococcal polysaccharide powder Type 9 (d9N) 10mg
Purified pneumococcal polysaccharide type 9N is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 9N can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
ATCC Thermotoga maritima; MSB8; genomic DNA
Genomic DNA isolated from Thermotoga maritima strain MSB8. This bacterial strain is also available as ATCC Catalog No. 43589™.
Eurofins Discoverx ChemiScreen GLP-1 Receptor Membrane Preparation, 1 vial. (HTS163M)
The ChemiScreen GLP-1 Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of GLP1R surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach or to screen for GPCR activity using GTPγS assays. Increased binding affinities or GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx PathHunter CHO-K1 MR Nuclear Translocation Cell Line, 2 vials. (93-0451C2)
The PathHunter MR Nuclear Translocation cell line is a stable, engineered cell line for use in studying drug candidates affecting NHR activation and nuclear translocation. This cell line enables assessment of ligand (e.g. aldosterone) based NHR activation via detection of resulting MR (mineralocorticoid receptor) nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged MR NHR and nuclear localized EA. Upon activation of MR, induced nuclear translocation leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/nhr.
Promocell GmbH PromoCell HSAEpC-c 500,000 Human Small Airway Epithelial Cells, cryopreserved
Primary Human Small Airway Epithelial Cells (HSAEpC) are isolated from the distal portion of the human respiratory tract in the 1 mm bronchiole area. They stain positive for cytokeratin.The distal respiratory tract mainly consists of pulmonary alveoli, which are spherical outcroppings of the respiratory bronchioles and are the primary sites of gas exchange with the blood. HSAEpC are qualified for functional studies to investigate disorders such as asthma or pulmonary inflammation.Our HSAEpC are now also available from HLA-typed and COPD/Asthma donors.Available formats:* Cryopreserved: Cryogenic vial containing 500.000 viable cells.* Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).
Promocell GmbH PromoCell HUtMEC Pellet from > 1 million Normal Human Uterine Microvascular Endothelial Cells
Cell pellet consisting of 1 million cells dissolved in 200µl RNAlater for subsequent RNA, DNA or protein analysis. Note: Cell pellets cannot be revived.Our Cell Pellets are stored in RNAlater – an aqueous protection solution that rapidly permeates the cells and stabilizes cellular DNA, RNA, and proteins and protects them from degradation. This makes our Cell Pellets very useful for a wide range of research applications like gene expression analysis, cell characterization studies, and protein characterization experiments.Each Cell Pellet is made from 1 million cells and is dissolved in 200 µl RNAlater. The Cell Pellets are produced from released cell lots and have the same characteristics, i.e. expression profile or cell type specific antigens. On request, viable cells from the same lot are available for cultivation.
Eurofins Discoverx ChemiScreen PAC1-long Receptor Stable Cell Line, 2 vials. (HTS114C)
The ChemiScreen PAC1-long Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PACAP) based activation of ADCYAP1R1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses ADCYAP1R1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of ADCYAP1R1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.