General Cell Lines and Cell Cultures
Abcam Luciferase Reporter Assay Substrate Kit - Renilla.
Luciferase Reporter Assay Substrate Kit - Renilla.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter CHO-K1 OXGR1 β-Arrestin Orphan GPCR Cell Line, 2 vials. (93-0693C2)
The PathHunter OXGR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. alpha-ketoglutaric acid) based activation of OXGR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OXGR1 and EA-tagged β-Arrestin-2. Activation of OXGR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 CCR3 β-Arrestin Cell Line, 2 vials. (93-0629C2)
The PathHunter CCR3 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL13/MCP-4) based activation of CCR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCR3 and EA-tagged β-Arrestin-2. Activation of CCR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 VIPR2 β-Arrestin Cell Line, 2 vials. (93-0317C2)
The PathHunter VIPR2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. VIP) based activation of VIPR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged VIPR2 and EA-tagged β-Arrestin-2. Activation of VIPR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 mEDNRB β-Arrestin Cell Line, 2 vials. (93-0602C2)
The PathHunter mEDNRB cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. endothelin-3) based activation of mEDNRB GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mEDNRB and EA-tagged β-Arrestin-2. Activation of mEDNRB stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CCR6 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0966C3)
The PathHunter CCR6 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of CCR6 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged CCR6. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting CCR6-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Paraffin Tissue Section Panel - Human Tumor Same Tumor Type, Different Donors (5 tissues), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures.The tissues are immediately put in liquid nitrogen after being excised, and then identified by a board-licensed pathologist. Patient demographic and disease related history data are available. he tissue sections are approximately 5-10 um thick.
Eurofins Discoverx PathHunter U2OS mPD-L1 Ligand Cell Line, 2 vials. (93-1159C3)
The PathHunter mPD-L1 Ligand cell line is a stable, engineered cell line designed as a companion product for use with mPD-1 Checkpoint Signaling Cell Lines. When co-cultured, the mPD-L1 expressed in this cell line will induce activity of mPD-1 receptors, which may be assayed through SH2 domain protein recruitment. The cell line included overexpresses mPD-L1 cell surface ligand. When co-cultured with the mPD-1 Checkpoint Signaling Cell Line, the mPD-L1 ligand binds to the checkpoint receptor, inducing receptor activity. This receptor activity leads to recruitment of the relevant SH2 domain protein to the checkpoint receptor inside the receptor cell line and production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/checkpoint.
ATCC Klebsiella pneumoniae; subsp. pneumoniae
Klebsiella pneumoniae subsp. pneumoniae strain [CIP 104216, NCIB 10341] was isolated from cow's milk. This whole-genome sequenced bacterial strain can be used in inhibition testing, disinfectant testing, quality control, and respiratory disease research.
Lonza Walkersville Mouse C57BL/6 Hepatocytes, Cryopreserved, Plateable
Cryopreserved C57BL/6 Mouse Hepatocytes, Plateable are specifically pre tested for metabolic activity of general Phase I and Phase II metabolism in suspension.They are tested for healthy morphology lasting 72 hours in monlayer sandwich culture.Applications:Drug metabolism in plated monolayer formatSpecies-species comparisonsGenomicsContent:1 x Cryopreserved ampule of C57BL/6 Mouse Hepatocytes (plateable format) containing > 5 million viable cells
iQ Biosciences Göttingen Minipig PBMCs, 10M cells/vial
High-quality, high-viability (> 80%) peripheral blood mononuclear cells (PBMCs) from the Göttingen minipig used for a wide variety of immunological, translational, and toxicity studies. All orders come with an iQ Certificate of Analysis.
iQ Biosciences Human Irradiated PBMCs, 100M cells/vial
High-quality, high-viability (> 80%) irradiated peripheral blood mononuclear cells (PBMCs) from healthy blood donors sourced from a world-renowned blood center. Used for a wide variety of immunology-based applications, including in-vitro immunoassays and ex-vivo applications. All orders come with an iQ Certificate of Analysis.The following donor requests can be accommodated if inventory is available: - Single or multiple donors for a particular product (SKU). Indicate the number of vials from each individual donor - Positive or negative for EBV or CMV (for healthy donors only) - Good responder or non-responder to tetanus antibody (for healthy donors only) - HLA types for Class I and Class II alleles (for healthy donors only) - Donor(s) with a higher percentage of the cells of interest (e.g., B cells, CD4+ cells, CD8+ cells, NK cells, etc.) - Gender, age, body mass index (BMI), or ethnicity
Amsbio LLC Lyophilized exosomes from Plasma of Healthy donors
Lyophilized exosomes from Plasma of Healthy donors
ATCC Quantitative Synthetic; Chlamydia trachomatis; LGV Type 1 DNA
Quantitative Synthetic Chlamydia trachomatis LGV Type 1 DNA can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load. Preparation includes fragments from MOMP, 16S rRNA, pmpH, dnaB, putative virulence plasmid integrase regions, and conserved hypothetical virulence plasmid protein.
Biotium CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: